Highlights Articles

Microbiomes modulate the local immune response, influencing immunotherapy response and toxicity
Immunotherapy has revolutionized the treatment of several cancers. However, it remains elusive why only some patients benefit from these treatments and why some patients experience immune-related adverse events (irAEs). More

Microbiomes modulate the local immune response, influencing immunotherapy response and toxicity

doi: 10.21037/atm-20-6427Immunotherapy has revolutionized the treatment of several cancers. However, it remains...

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Resistance to anti-PD-1 immunotherapy can be attributed to the gut microbiome
Immunotherapies (Immune Checkpoint Inhibitors, ICI) have become a powerful therapeutic strategy for treating a variety of cancers. It is a very exciting area, but with challenges. Indeed, the patients’ response to these therapies is often heterogeneous and not durable, with only 20 to 40% of patients actually responding. More

Resistance to anti-PD-1 immunotherapy can be attributed to the gut microbiome

DOI: 10.1126/science.aan4236 DOI: 10.1126/science.aao3290 DOI: 10.1126/science.aan370Immunotherapies (Immune...

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